High-throughput experimentation
- a modular course

Module II: Fundamental aspects of combinatorial chemistry

 March 18 - 20, 2014, Universität des Saarlandes, Saarbrücken/Germany

 Apart from a theoretical part focusing on Design of Experiment (DoE) and the basics of the experimental modules presented in the second, practical part, this module has the objective to introduce a modular course that has been designed to allow an affordable implementation of combinatorial and high-throughput experiments in academic teaching laboratories. Currently, the course consists of five experimental modules. These include a Split & Pool experiment for catalytic screening with mixed metal oxides, a combinatorial synthesis of an azo dye library, an in-vestigation of ternary phase and Kahlweit fish diagrams for microemulsions, the DoE and automatization of parallel Sonogashira-Hagihara cross-couplings and a wettability gradient library synthesis of semifluorinated organosilanes.

This module gives a good overview on the basic methodology and introduces its applications.

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